All of our servers are running at 800 x 600 and this works fine for MailEnable with the exception on two dialogs. The SMTP properties dialog and the DKIM Settings dialog are just slightly to big to fix on the screen. With just a couple of tweaks and no programming this could be remedied. See images below.
http://bak.wwmerchant.com/me_smtp.png
http://bak.wwmerchant.com/me_dkim.png