SYMPTOMS

Error: The Template Persistent Cache initialization failed for Application Pool 'MailEnableAppPool' because of the following error: Could not create a Disk Cache Sub-directory for the Application Pool. The data may have additional error codes..

The problem is there are two user groups (IIS_WPG and NETWORK SERVICE) that don't have permissions set on the following three folders:

• %systemroot%\Help\IISHelp\Common
• %systemroot%\System32\Inetsrv\ASP Compiled Templates
• %systemroot%\IIS Temporary Compressed Files
• %systemroot% is usually C:\windows or C:\winnt

For "%systemroot%\Help\IISHelp\Common" you should grant both groups; Read and Execute, List Folder Contents, and Read permissions.

For "%systemroot%\System32\Inetsrv\ASP Compiled Templates" and "%systemroot%\IIS Temporary Compressed Files" you should grant both groups full control.

You will need to restart IIS once you have made the above-mentioned changes. Once IIS has been restarted, you should do as follows:

1. Click Start, click Run, type Services.msc, and then click OK.
2. Right-click IIS Admin, and then click Restart.

If this is a domain controller:

http://support.microsoft.com/kb/332097

REFERENCES

http://support.microsoft.com